As time passes, the skin undergoes changes, becoming damaged and showing signs of aging. Despite claims made by cosmetic products and a healthy lifestyle, the deeper layers of the skin start to deteriorate. They lose important components like hyaluronic acid, collagen, and vitamins. Through Mesotherapy, we can reverse this aging process by replenishing the skin with collagen, vitamins, and minerals.
Treatment Duration
Lasts up to 12 months
Results Seen
Minimal to no downtime
What is Traditional Mesotherapy?
Mesotherapy was initially developed in the 1950s by Dr. Michel Pistor from France.
This technique, known for rejuvenation, involves micro-injections of vitamins, antioxidants, enzymes, and plant extracts to tighten and rejuvenate the skin, improve hair quality, eliminate excess fat, and combat cellulite. Fine needles are used to administer injections in the middle layer of the skin, targeting underlying issues such as inflammation and poor circulation that contribute to skin damage.
Prior to Mesotherapy, issues like stubborn fat deposits, wrinkles, and pigmentation abnormalities can be observed.
Post-treatment, improvements are visible in dull, tired-looking skin, reduction of wrinkles, and fat reduction. In cases of alopecia, hair growth can be promoted through this procedure.
This research is affiliated with the Department of Periodontology, Faculty of Dental Sciences, Ramaiah University of Applied Sciences in Bengaluru, Karnataka, India. The study was received on June 22, 2020, revised on September 17, 2020, accepted on September 24, 2020, and published in the May-June 2021 issue. This journal is open access and distributed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License.
Traditional Mesotherapy has been used for decades as a popular cosmetic treatment that targets various skin and hair concerns. The procedure involves injecting a mixture of vitamins, antioxidants, enzymes, and plant extracts directly into the skin to address specific issues such as inflammation, poor circulation, and excess fat deposits.
Patients often witness significant improvements in their skin’s appearance, including reduced wrinkles, increased firmness, and a more radiant complexion. In addition, Mesotherapy can also stimulate hair growth and combat conditions like alopecia.
Abstract
Background:
Mesotherapy includes local intradermal therapy (LIT) using small quantities of biologically active substances in the affected area. Vitamin C, a powerful antioxidant, can control inflammation and enhance tissue healing.
Materials and Methods:
Following phase I therapy, five patients with persistent chronic gingival inflammation received Vitamin C injections and were regularly evaluated for inflammation resolution.
Results:
Clinical assessments showed a significant improvement in inflammation at the injected sites during follow-up appointments.
Conclusions:
LIT with Vitamin C complements scaling and root planing in effectively managing persistent gingival inflammation.
Keywords: Anti-inflammatory agents, inflammation, mesotherapy, periodontal therapy, Vitamin C
INTRODUCTION
Gingival inflammation presents varying signs and symptoms based on severity and response to treatment. Vitamin C acts as an antioxidant, regulating inflammation and promoting tissue repair. Mesotherapy, a minimally invasive procedure, provides targeted intradermal therapy with biologically active substances.
Research has shown that vitamin C plays a crucial role in maintaining gum health by reducing inflammation and supporting collagen production. In addition, mesotherapy has been increasingly utilized in dentistry to deliver therapeutic agents directly to the affected tissues, providing targeted and effective treatment for gum inflammation.
MATERIALS AND METHODS
Patients meeting specific criteria received Vitamin C injections for persistent gingival inflammation. The study protocol was approved by the ethics committee, and patients were provided oral hygiene instructions and full-mouth scaling and root planing before injections.
Figure 1.
Pre-treatment photo of case 1
All injections were administered by the same practitioner using insulin syringes. Patients received prescribed analgesics post-treatment if needed.
Figure 2.
(a and b) Injection of Vitamin C using an insulin syringe
The same dosage was repeated until inflammation subsided. Patients were re-evaluated after the second injection, with plaque and sulcus bleeding index recorded throughout.
RESULTS
Inflammation showed improvement in all cases following two injections. Patients responded well to treatment without side effects or the need for analgesics.
Figure 3.
Case 1 – One-week follow-up after the first dose of Vitamin C
Figure 4.
All patients exhibited a significant reduction in plaque index scores, with decreased sulcus bleeding index scores post-injections.
DISCUSSION
Chronic inflammation persists despite oral hygiene measures. Non-surgical approaches are now preferred over antibiotics or surgical options with potential adverse effects.
In this study, a 100% reduction in gingival inflammation was clinically observed, along with improvements in color, form, and SBI scores from the average baseline within a 2-week period [Figure 5].
Figure 5.
(a-d) Pre-treatment (e-h) follow-up after Vitamin C injection
Single or multiple intraepidermal Vitamin C injections can be given based on the severity of the condition, with a one-week interval between doses. Careful management of inflamed tissues is crucial to prevent tearing and tissue necrosis in areas with thin gingival biotype.
These findings align with the study by Yussif et al. that highlighted improved gingival health with antioxidant usage.
Mammucari et al. also noted promising results in treating localized inflammation using mesotherapeutic techniques with anti-inflammatory agents.
Tissue antioxidants decrease rapidly during inflammation, leading to increased production of free radicals at the site. Hence, higher doses of antioxidants like Vitamin C are necessary. Antioxidants stabilize free radicals by sharing electrons with them. Administering high systemic doses to reach adequate levels at the inflammation site can be detrimental. Local injections effectively provide the required doses.
Local administration of Vitamin C is superior to topical use in dentifrices or gels, as observed in earlier studies by Daniels et al. and Shimabukuro et al., due to its water solubility and superficial penetration. Topical Vitamin C drawbacks include delayed improvement, lack of substantivity on oral tissues, reduced absorption, and instability under various conditions.
Vitamin C plays a crucial role as an enzyme cofactor in collagen formation, essential for connective tissue synthesis and mucosal healing. Yussif et al. reported reduced epithelium thickness and inflammatory cells, along with increased subbasal capillaries with locally injected Vitamin C.
CONCLUSIONS
The study concludes that Vitamin C mesotherapy has a synergistic effect with SRP in addressing persistent gingival inflammation. Further research with longer follow-up periods is recommended to validate these outcomes.
Financial support and sponsorship
The authors would like to acknowledge the financial support provided by [insert name of funding organization or grant].
Conflicts of interest
The authors declare that there are no conflicts of interest reported in relation to this study.
REFERENCES
Articles from the Journal of Indian Society of Periodontology are provided here with the courtesy of Wolters Kluwer — Medknow Publications
1. Hydrate, rejuvenate, and tighten the skin
2. Reduce the appearance of fine lines and wrinkles
3. Minimize acne and acne scars
4. Enhance skin radiance and hydration
5. Restore the skin
Cost of a one-time Mesotherapy treatment – $150
Before After
Before After
What is Mesotherapy?
Mesotherapy involves injections of vitamins, enzymes, hormones, and plant extracts to rejuvenate the skin, tighten it, and reduce excess fat.
This technique uses fine needles to inject a series of substances into the middle layer of the skin (mesoderm) to correct underlying issues such as poor circulation and inflammation causing skin damage.
The cocktail of substances used in Mesotherapy can contain over 50 active ingredients to nourish, repair, and rejuvenate the skin.
Side effects may include bruising, reaction to the injected substances, infection, inflammation, and swelling.
Mesotherapy is a popular cosmetic procedure that stimulates skin regeneration and provides custom-selected nutritional preparations to address individual patient needs. Both facial and hair Mesotherapy treatments are available, tailored to specific concerns.
What is mesotherapy?
Facial mesotherapy aims to restore skin elasticity and firmness, even out the complexion, enhance facial contours, and reduce wrinkles. It can also target hyperpigmentation, scars, and stimulate hair follicles in hair loss treatments.
Mesotherapy involves injecting a combination of vitamins, minerals, amino acids, and hyaluronic acid into the mesoderm (middle layer of skin) to nourish and rejuvenate the skin. This treatment can improve skin texture, hydration, and overall appearance. Mesotherapy is a minimally invasive procedure that can be done in a dermatologist’s office with little to no downtime.
What is mesotherapy and how does the procedure proceed?
Needle mesotherapy and micro-needle therapy are well-known methods that utilize fine needles or special devices for injections. These procedures help in the regeneration and multiplication of skin cells at a faster rate. Needle therapy allows concentrated solutions to target specific problem areas effectively.
Mesotherapy is a non-invasive procedure that involves injecting small amounts of various substances such as vitamins, minerals, and amino acids into the mesoderm, or middle layer of the skin. These injections stimulate the production of collagen and elastin, improving skin firmness and elasticity.
The procedure generally takes around 30 minutes to an hour, depending on the area being treated. Patients may experience minimal discomfort during the injections, but any pain is usually well-tolerated. After the procedure, patients may notice immediate results, such as increased hydration and a more radiant complexion.
Overall, mesotherapy is a safe and effective treatment for a variety of skin concerns, including aging, acne, and hair loss. Consult with a qualified healthcare provider to determine if mesotherapy is right for you.
When to perform needle mesotherapy? Indications
Needle mesotherapy is recommended by specialists for various skin issues, including signs of aging, loss of facial contour, skin sagging, loss of elasticity, tired-looking skin, dehydration, dark circles under the eyes, pigmentation, scars, cellulite, seborrhea, stretch marks, and hair loss. Depending on the specific problem, different solutions can be used during treatment. For example, Vitamin C mesotherapy targets hyperpigmentation, collagen or retinol mesotherapy is chosen for wrinkles and loss of elasticity, while hyaluronic acid mesotherapy is selected to restore skin radiance and provide adequate moisture. Platelet-rich plasma mesotherapy, derived from the patient’s blood, is another popular method that delivers regenerating and stimulating components to the skin.
When will needle-free mesotherapy be a good choice?
- Stimulating skin for collagen, elastin, and hyaluronic acid production
- Thickening and increasing skin elasticity
- Hydrating and nourishing the skin
- Reducing scars and stretch marks
- Diminishing hyperpigmentation, dark circles, and dilated blood vessels
- Improving skin tone and overall appearance
Non-injection mesotherapy is suitable for individuals looking to maintain skin health or prevent aging processes. It acts as a preventive treatment to delay aging signs by promoting the production of key elements such as collagen, elastin, and hyaluronic acid in the skin, usually started after 20 years of age when skin processes begin to slow down.
Needle-free mesotherapy is also a good choice for individuals who are afraid of needles or have a low pain tolerance. It offers a non-invasive alternative to traditional mesotherapy treatments, providing similar results without the discomfort associated with injections.
Furthermore, needle-free mesotherapy can be a convenient option for busy individuals who do not have time for downtime or recovery periods. The treatment is quick and painless, allowing patients to resume their daily activities immediately after the session.
In addition, needle-free mesotherapy can be a cost-effective solution for those looking to improve their skin without breaking the bank. With a series of treatments, patients can achieve noticeable improvements in their skin texture, tone, and overall appearance without the high cost of surgical procedures.
How many mesotherapy treatments need to be performed to achieve the desired effect?
Many individuals considering mesotherapy often wonder about the treatment’s effectiveness. The results can vary depending on the severity of issues, the patient’s skin regeneration rate, and genetic factors. While some effects may be visible after a single session, a recommended course typically involves 3-5 sessions weekly. To achieve optimal results, it’s crucial to seek mesotherapy from experienced professionals who can evaluate skin problems accurately and use certified products. At OT.CO Clinic, innovative mesotherapy treatments are available for various skin conditions and hair loss. Following a treatment series, maintaining daily skincare routines and periodically repeating sessions are essential to sustain the effects.
Conclusion
Mesotherapy is a powerful and versatile treatment for skin and hair, offering transformative benefits from improving elasticity to stimulating hair growth. Whether needle-based or non-injection methods are chosen, outcomes depend on the specific issue, solution used, and the expertise of the practitioner. Combining procedures with regular care and follow-up visits helps maintain the effects. Mesotherapy is a minimally invasive procedure providing targeted solutions for healthier, rejuvenated skin and hair. Consultation with professionals ensures safe and optimal results, offering a smart, customizable approach to enhance overall skin and hair health.