Our clinic specializes in innovative Mesotherapy treatments in the UK & Europe. Mesotherapy is a natural, non-invasive injection therapy that hydrates, nourishes, and revitalizes the skin by boosting collagen and elastin production.
By delivering essential nutrients to the middle skin layer, Mesotherapy enhances the appearance of dull, tired skin, superficial wrinkles, and pre/post-operative skin conditions.
{Innovative Mesotherapy Techniques}
Our Mesotherapy procedures involve superficial injections performed manually or with advanced injection devices for larger treatment areas. We are proud to introduce the Teosyal Pen for Mesotherapy and Dermal Filler treatments in the UK.
The Teosyal Pen from Juvaplus utilizes a motorized mechanism to inject hyaluronic acid for correcting wrinkles and depressions.
In addition to the Teosyal Pen, we also offer other innovative mesotherapy techniques such as microneedling, radiofrequency, and ultrasound-assisted mesotherapy. These techniques can help improve skin texture, reduce cellulite, and promote overall skin rejuvenation.
Our team of experienced professionals customize each mesotherapy treatment to address the specific needs and concerns of our patients, ensuring optimal results and patient satisfaction.
{Reviving Your Skin Naturally}
Skin Rejuvenation
Mesotherapy rejuvenates facial, neck, décolletage, and hand skin to restore its youthful glow. By stimulating collagen production, the treatment effectively reduces fine lines, wrinkles, scars, and enhances skin health.
Mesotherapy is a versatile treatment that can effectively address various aesthetic and medical concerns.
Learn more about Mesotherapy here.
{Tailored Mesotherapy Solutions for Every Age}
Mesotherapy offers effective skin rejuvenation solutions at any age with customized formulas for optimal results.
In different age groups, Mesotherapy helps maintain youthfulness, corrects signs of skin aging, and visibly enhances skin quality in just 2-3 sessions.
Results may vary based on individual body types and the specific condition being treated.
{Enhancing Skin Rejuvenation with Complementary Procedures}
Mesotherapy is a minimally invasive procedure that involves injecting vitamins, minerals, and amino acids into the mesodermal layer of the skin. This treatment is designed to rejuvenate the skin and improve its overall appearance.
In addition to mesotherapy, complementary procedures such as chemical peels, microdermabrasion, and laser treatments can be used to further enhance skin rejuvenation. Chemical peels help to exfoliate the skin and improve its texture, while microdermabrasion helps to remove dead skin cells and stimulate collagen production. Laser treatments can target specific skin concerns such as pigmentation, fine lines, and wrinkles.
When combined with mesotherapy, these complementary procedures can provide more comprehensive results and help patients achieve smoother, firmer, and more radiant skin. It is important to consult with a qualified skincare professional to determine the best combination of treatments for individual skin concerns.
{Evaluating the Clinical and Histological Effects of Mesotherapy}
{Mesotherapy: The Rejuvenating Treatment}
Mesotherapy, also known as “biorejuvenation” or “biorevitalization,” improves skin aging symptoms by injecting a blend of multivitamins and natural extracts for skin rejuvenation.
{Research Findings on Mesotherapy}
An assessment of mesotherapy’s impact on periorbital wrinkles and skin histology revealed no significant changes in a study group. The volunteers underwent mesotherapy sessions with no observable clinical or histological improvements.
{Evaluating Collagen Types and Elastin}
Six participants received mesotherapy injections over three months without notable changes in collagen types and elastin levels. The study concluded that mesotherapy did not significantly alter skin texture or appearance.
{Assessing Skin Rejuvenation Outcomes}
The study highlighted the limited impact of mesotherapy on histological changes or clinical enhancements for skin rejuvenation.
{Understanding the Skin Aging Process}
Aging affects all organs, including the skin, leading to visible changes like thinning, dryness, and wrinkling. Mesotherapy, developed by Michel Pistor, utilizes transdermal injections to rejuvenate and tone the skin using a blend of vitamins, enzymes, hormones, hyaluronic acid, and plant extracts.
Despite mesotherapy’s popularity for skin revitalization, its safety and efficacy lack scientific validation. This study aims to scrutinize the clinical effects and histological alterations associated with mesotherapy for skin rejuvenation.
{Clinical Study Overview}
{Clinical Evaluation of Mesotherapy Treatments}
Six female volunteers completed a three-month mesotherapy program for periorbital wrinkles. After six treatment sessions at two-week intervals, some participants noted improved skin radiance, but not significant changes in skin elasticity or wrinkles.
The mesotherapy injections, administered using a meso-system gun, included a multivitamin solution and high-viscosity hyaluronic acid. Skin biopsies were obtained for histological analysis before treatment, and at three and six months post-treatment.
{Histological Assessment Procedures}
The samples underwent staining to evaluate collagen types I and III, elastin, and epidermal thickness using advanced imaging software. The study aimed to quantify changes in skin components following mesotherapy treatment.
{Study Results}
{Progression of Mesotherapy Treatment Over 3 Months}
All six volunteers completed the mesotherapy program without adverse effects. While some observed improved skin radiance, no significant changes in skin elasticity or wrinkles were noted. The study did not reveal a statistically significant impact of mesotherapy on skin texture, elasticity, or wrinkles.
Figure 1.
{Impact of Mesotherapy on Collagen Types}
{Evaluating Mesotherapy’s Influence on Collagen Types I and III}
The study explored the effects of intradermal multivitamin injections on skin rejuvenation by stimulating fibroblasts to produce collagen and elastin. Immunohistochemical staining indicated no substantial changes in collagen types I and III before and after the mesotherapy program.
Table 1.
The results of a three-month mesotherapy regimen on six volunteers.
Figure 2.

Quantitative analysis showed no significant differences in collagen type VII and newly synthesized collagen over time. Collagen VII levels remained consistent without significant changes.
Figure 3.
Elastin levels did not significantly change immediately after mesotherapy or three months post-treatment. Tropoelastin synthesis did not show notable differences before or after mesotherapy.
{Evaluating the Efficacy of Mesotherapy}
Mesotherapy is a cosmetic technique designed to rejuvenate aging skin, performed by both medical and non-medical experts. While numerous mesotherapy ingredients are FDA-approved, concerns persist regarding treatment efficacy, protocols, pharmacokinetics, and safety.
Despite reported improvements in wrinkles, skin elasticity, and texture, concrete evidence supporting mesotherapy’s efficacy for skin rejuvenation is scarce. The duration of its effects, whether temporary or permanent, remains uncertain.
This study aimed to evaluate the clinical effects and histological changes associated with mesotherapy for skin rejuvenation, highlighting the need for further research on its safety and efficacy.
Special thanks to the Cultural and Educational Bureau of Egypt for their financial support and Alicia Dowling for manuscript review. Funding was generously provided by the Cultural and Educational Bureau of Egypt and the National Institutes of Health.